CMDR Members


 
Robert E. W. Hancock
(Director, CMDR)
Professor,  Dept Microbiology & Immunology, Faculty of Science.
email
web page
Pathogenomics. Antibiotic action and resistance mechanisms. Outer membranes of Gram negative bacteria, especially Pseudomonas aeruginosa Cationic Antimicrobial Peptides: Mechanisms of action, development as novel antimicrobials and role in innate immunity.
David P. Speert
(Associate Director, Microbial Diseases, CMDR
Professor, Dept. of Pediatrics, 
Faculty of Medicine. 
email
web page
 
Studies of bacterial infection of the lung, particularly in patients with cystic fibrosis. Specfic research projects involve attempts to elucidate virulence determinants of Pseudomonas aeruginosa and Burkholderia cepacia and to clarify the role of macrophages in host defense of the lung
W. Robert McMaster
(Associate Director, Immunity, CMDR)
Head, Medical Genetics Dept, Faculty of Medicine. 
email
web page
Immunogenetics, Molecular immunology, Leishmania, Mycobacterium tuberculosis. 
Ninan Abraham
Asst Professor,  Dept Microbiology & Immunology, Faculty of Science.
email

webpage

Cytokine regulation of lymphocyte control by signalling pathways that mediate proliferation and survival
Yossef Av-Gay
Assoc Professor, Dept. of Medicine, Faculty of Medicine.
email
web page
Microbial pathogenicity.  Molecular genetics of microorganisms.  Identification of targets for drug design. 
Fiona S.L. Brinkman
(Associate member CMDR)
Asst Professor, Dept Molecular Biology & Biochemistry, Simon Fraser University
email
web page
Pathogen bioinformatics. Evolution of pathogenicity. Prediction of the subcellular localization of proteins, particularly cell surface-exposed proteins.
Robert C. Brunham
Director, UBC Centre for Disease Control, Medical Director, BC Centre for Disease Control. 
email
web page
Epidemiology and immunology of sexually transmitted diseases, especially Chlamydia trachomatis, and their impact on reproduction and genetics.
Janet K. Chantler
Associate Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine
email

webpage

Viral pathogenesis and persistence. Rubella and Coxsackie virus B.
Anthony W. Chow
Professor, Dept. of Medicine,
Faculty of Medicine.
email
web page
Molecular pathogenesis/clinical spectrum of staphylococcal toxic shock syndrome.  Mucosal immunity of the female genital tract.  Heat shock protein gene in microbial identification, phylogeny, pathogenesis and serodiagnosis.
Julian E. Davies
Professor, Dept. Microbiology & Immunology, Faculty of Science.
email

webpage

Function/regulation of resistance transfer factors. Origin/evolution of antibiotic resistance genes.  Antibiotics as effectors of self-splicing reactions.  Gene transfer between distantly related microbes. Application of Microbial diversity. 
Simon R.M. Dobson
Clinical Assoc Professor, 
Pediatrics Dept., 
Faculty of Medicine 
email
Neonatal infections, study of immunogenicity & vaccine implementation, Hep B & Influenza vaccine studies, infections in childhood.
Vincent Duronio
Professor, Dept Medicine,
Faculty of Medicine.
email
web page
Cytokines and receptors, Signal transduction, Inflammatory cells
Jan Dutz
Assoc Professor, Div Dermatology, Faculty of Medicine
email
web page
Skin as an immune organ; Transcutaneous immunization, Antigen presentation, Cytotoxic T-cells, Vaccine design, apoptosis and immunity
Brian E. Ellis
Professor and Assoc Director, Michael Smith Laboratories and Faculty of Agriculture
email
web page
Plant biochemistry and biotechnology.
Rachel Fernandez
Assoc Professor, Dept Microbiology & Immunology, Faculty of Science.
email
web page
Molecular pathogenesis of Bordetella pertussis.
B. Brett Finlay
Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.
email
web page
Host-parasite interactions.  Salmonella as a model intracellular pathogen.  Enteropathogenic and enterohemorrhagic E. coli. Epithelial cell signal transduction involved in bacterial invasion. Live oral vaccines. 
Erin Gaynor
Asst Professor, Dept Microbiology & Immunology, Faculty of Science.
email

webpage

Functional pathogenomics of Campylobacter pathogenesis.
Shirley Gillam
Professor, Dept. of Pathology and Laboratory Medicine,
Faculty of Medicine.
email
 
Molecular biology of Rubella Virus. 
Mike R. Gold
Assoc Professor, Dept Microbiology & Immunology, Faculty of Science.
email
web page
Signal transduction by the B lymphocyte antigen receptor (BCR). 
Mike Grigg
Asst Professor, Dept. of Medicine, Faculty of Medicine
email

webpage

Toxoplasma pathogenomics
Philip Hieter
Director, Michael Smith Laboratories and Professor, Dept. of Medical Genetics, Faculty of Medicine.
email
web page
Molecular Genetics.  Chromosome transmission.  Centromere function.  Mitosis.  Cell division cycle.  Mechanism of aneuploidy.  Genome analysis. 
Judith L. Isaac-Renton
Professor, Dept Pathology & Laboratory Medicine,
Faculty of Medicine.
email
web page
Tropical diseases and medical parasitology.  Pathogenesis, epidemiology and etiology of giardiasis.  Cryptosporidiosis and toxoplasmosis. 
Francois Jean
Director, Laboratory for Antimicrobial Therapy, CIHR/Health Canada Scholar, Asst Professor, Dept Microbiology & Immunology, Faculty of Science.
email
web page
Host-virus interactions: Virogenomics and viroproteomics of Flaviviridae (Hepatitis C virus) and Herpesviridae (HHV-6, -7 and 8) and Coronaviridae (SARS-CoV). Identification and development of new protein-based antiviral agents.
Wilf Jefferies
Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.
web page Functions of iron transport molecules expressed at the brain endothelium; Viral antigen processing and presentation; Evasion of the host immune system by Human Adenoviruses.
Pauline Johnson
Professor, Dept Microbiology & Immunology, Faculty of Science.
email
web page
Molecular mechanisms that regulate the T cell immune response, immune cell adhesion and migration at sites of inflammation
Patrick Keeling
Assistant Professor & Scholar, 
Dept. of Botany and Canadian Institute for Advanced Research 
Faculty of Science 
email
web page
Evolution of protozoa with emphasis on the origin of intracellular parasites apicomplexa and microsporidia, effects of symbionts on evolution of eukaryotic genomes, and understanding eukaryotic evolution through comparative phylogeny.
Paul Keown
Professor & Div. Head, Nephrology, Dept Medicine, Faculty of Medicine
email

webpage

Transplantation, Graft rejection, Tolerance, Autoimmunity
James W. Kronstad
Professor, Michael Smith Laboratories and Dept Microbiology & Immunology, Faculty of Science.
email
web page
Fungal sexual development.  Plant-Microbe interactions.  Fungal morphogenesis and pathogenicity.
Hannu S. Larjava
Professor, Dept Oral Biological & Medical Sciences, Faculty of Dentistry. 
email
web page
Integrins of wound healing. 
George A. Mackie
Professor, Dept Biochemistry & Molecular Bioloy, Faculty of Medicine & Assoc VP Academic Planning
email
web page
mRNA turnover, ribosomal assembly, and viral replication. 
Linda Matsuuchi
Assoc Professor, Dept Zoology, Faculty of Science
email
web page
Intracellular trafficking and cell signaling of membrane receptors; Structure and function of the antigen receptor on B lymphocytes.
Deborah Money
Clinical Instructor
email

webpage

 
Muhammad Morshed
Clinical Assistant Professor, 
Dept Pathology, Faculty of Medicine, and Head, Zoonotic Diseases & Emerging Pathogens, 
BCCDC 
email
web page
Helicobacter spp., Borrelia spp., Treponema pallidum, and zoonotic diseases.
Devki Nandan
Research Assoc, Dept Medicine,
Faculty of Medicine.
email
web page
Biochemistry and cell biology of host-pathogen interactions, emphasis on cell-signalling associated events in human macrophages. 
Corrine S. L. Ong
Asst Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine.
email
web page
Structure, function and purification of immunogenic membrane proteins.  Vaccine Immunology.  Molecular bio-typing and fingerprinting of endemic/epidemic isolate of protozoans.  Gastrointestinal and blood protozoans. 
David M. Patrick
Assoc Professor, Dept Medicine and Director, Communicable Disease Epidemiology, BC Centre for Disease Control
email

webpage

HIV Epidemiology; Sexually transmitted diseases; Control of communicable diseases.
Neil E. Reiner
Professor & Division Head, Infectious Diseases, Dept Medicine,
Faculty of Medicine.
email
web page
Mononuclear phagocyte activation and cell signalling, cellular and molecular aspects of immunoregulation during chronic intracellular infection. 
Michael L. Rekart
Clinical Assoc Professor, Dept Medicine and Director, STD Clinic, BCCDC
email

webpage

HIV; Epidemiology; Screening; Clinical trials.
David W. Scheifele
Professor, Dept Pediatrics, & Director Vaccine Evaluation Centre, Faculty of Medicine.
email
web page
Vaccine evaluation research; vaccine policy formulation; vaccine program evaluations. 
Kirk Schultz
Assoc Professor, Dept Pediatrics,
Faculty of Medicine
email

webpage

Pediatric oncology, Hematopoietic transplantation
Richard W. Stokes
Assoc Professor, Dept Pediatrics, 
Faculty of Medicine.
email
web page
Mycobacterial pathogenesis.  Interaction of mycobacteria with macrophages. 
Novel therapeutics for mycobacterial infections.
Natalie C. J. Strynadka
Professor, Dept Biochemistry, Faculty of Medicine. 
email
web page
Antibiotic resistance; LexA repressor; Antibiotic design; Inhibitor Design/BLIP. 
Hung Sia Teh
Professor, Dept Microbiology & Immunology, Faculty of Science.
email
web page
Role of RasGRP1, TNFR2 and CD30 in T cell function; Mechanism of induction of dermatits in a mouse model; Role of self-specific CD8 T cells in regulating tumor growth.

Charles J. Thompson

Professor and Head, Department of Microbiology and Immunology, University of British Columbia Life Sciences Centre.

email
web page
Regulation of bacterial gene expression. Transcriptional regulators that program antibiotic biosynthesis and resistance in Streptomyces. Innate antibiotic resistance and developmental states in Streptomyces and related Mycobacteria.
VV-Jukka Uitto
Professor, Oral Biological & Medical Science, Faculty of Dentistry 
email Studies on collagenolytic activity in periodontal diseases, oral bacteria & eptithelial cell behaviour in wound infection & healing, elastase inhibitors
J. Douglas Waterfield
Professor
Dept Oral Biological & Medical Sciences, Faculty of Dentistry
email

webpage

Pediodontal disease; immunology; Cytotoxic T cells; Systemic Lupus; Erythematosis; Rheumatoid arthritis and Sjorgreus syndrome.
Decheng Yang
Assoc Professor, Dept Pathology & Laboratory Medicine, Faculty of Medicine.
email
web page
Coxsackievirus replication and pathogenesis.  Host gene response to viral infections.  Development of anti-virus drugs and DNA vaccine of enterovirus. 

Centre for Microbial Diseases and Immunity Research
Copyright © CMDR

Updated March 2013